According to the constructed network, EGFR tyrosine kinase inhibitor resistance, PI3K-Akt signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, hemical carcinogenesis-receptor activation, JAK-STAT signaling pathway, and MicroRNAs in cancer were identified as the important pathways of CUR effects on TNBC. The gene discussed is CD274; the disease is cancer.