PDHA1 and cancer: Figure 1D showed stage-specific change of PDHA1 in eight tumor types, including KIRC, KIRP, BRCA, THCA, PAAD, testicular germ cell tumors (TGCTs), and esophageal carcinoma (ESCA). In other cancers, there was no clear association between the PDHA1 expression and patients’ stage (Supplementary Figure S1C).