CALCA and anaphylaxis: C-reactive protein, IL6, and KC concentrations were significantly higher in the critical illness group, compared to the anaphylaxis (CRP P < 0.0001, IL6 P < 0.001, KC P = 0.015) and healthy groups (CRP P < 0.0001, IL6 P < 0.0001, KC P < 0.0001) (Figure 3; Supplementary Table 1).