CCL2 and anaphylaxis: Both IL-10 and CCL2 concentrations were significantly higher in the anaphylaxis group (IL10 P < 0.0001, CCL2 P = 0.007) and the critical illness group (IL10 P = 0.007, CCL2 P < 0.001), compared to the healthy group (Figure 3; Supplementary Table 1).