Furthermore, EST12 KO strain (H37RvΔEST12) infection decreased the expression of Myc protein in RAW264.7 cells compared with WT H37Rv and the complementary strain H37RvΔEST12::EST12 (H37RvΔEST12 strain rescued with EST12) infection (Figures 1F; S1E, F). This evidence concerns the gene MYC and infection.