RT-qPCR indicated that HDGF and NRAS were overexpressed in OC, while NR1D1 and PSMD6 were underexpressed (Supplementary Figure 4C). We also used the HPA database to explore the differences in protein levels of the four immune genes between normal and tumor tissues (Supplementary Figure 4D). The gene discussed is NR1D1; the disease is neoplasm.