We further performed immunohistochemistry to externally verify the genes for METTL1, EIF3D, NUDT11, NUDT16, EIF4A1, IFI44, and CYFIP1 (https://www.proteinatlas.org/); the results showed that there were significant differences between ccRCC tissues and normal tissues (Supplementary Figure S3). The gene discussed is CYFIP1; the disease is nonpapillary renal cell carcinoma.