NUDT16 and nonpapillary renal cell carcinoma: We further performed immunohistochemistry to externally verify the genes for METTL1, EIF3D, NUDT11, NUDT16, EIF4A1, IFI44, and CYFIP1 (https://www.proteinatlas.org/); the results showed that there were significant differences between ccRCC tissues and normal tissues (Supplementary Figure S3).