Subsequently, we utilized the Wilcoxon rank-sum test to compare the mRNA expression levels of GSDM genes in distinct cancer types using both malignant tumor specimen and adjacent normal samples with an adjusted cutoff value of p < 0.05 (Figures 1B–H) (*p < 0.05, **p < 0.01, ***p < 0.001). Here, GSDMA is linked to neoplasm.