The positive rates of vimentin (P < 0.001 and P < 0.001), P504S (P = 0.003 and P = 0.005) and RCC (P < 0.001 and P = 0.002) in PRNRP were significantly lower than those in type I and type II PRCC, while GATA3 was expressed exclusively in PRNRP. The gene discussed is PRCC; the disease is renal cell carcinoma.