These results showed that TIGIT blocker introduction in MWA could up‐regulate the expressions of CXCL9 and CXCL10 in TAMs, boost CXCR3 expression in T cells, and promote CD8+ TILs activation and infiltration, which may inhibit tumor growth and enhance anti‐tumor immunity.[151] Furthermore, to explore the mechanism, some scholars used image‐guided ablation (IGA) to analyze the plasma protein profile and shed light on the principle including molecular signaling pathway after small renal tumor treatment. The gene discussed is CXCL9; the disease is neoplasm.