S100A9阳性的骨髓源性抑制细胞(myeloid-derived suppressor cells, MDSCs)可以被招募到脑组织中,构造出适合肿瘤种植的微环境,在脑转移瘤的形成中起着重要作用。贝伐珠单抗可以减少NSCLC患者外周血中S100A9阳性MDSCs,有效延缓脑转移[23]。. This evidence concerns the gene S100A9 and non-small cell lung carcinoma.