Autosomal dominant PKD (ADPKD) is the most common form of the disease, affecting ∼1:800 people, and is caused by mutations in PKD1 and PKD2, which encode polycystin-1 (PC-1) and PC-2, respectively (Grantham, 2003; Harris and Torres, 2014). Here, PKD1 is linked to autosomal dominant polycystic kidney disease.