PKC members play an antiviral role during infection by viruses (such as Rift Valley fever virus [RVFV], herpes simplex virus 1 [HSV-1], human papillomavirus 8 [HPV-8], and CHIKV) or promote infections by many viruses (such as HIV-1, MVM, and WNV). This evidence concerns the gene PRRT2 and infection.