Gene set enrichment analysis (GSEA) revealed significant enhancement of interferon (mLNs, NES = 3.13, FDR q value < 10−6; pLNs, NES = 3.21, FDR q value < 10−6) and inflammatory response pathways (mLNs, NES = 2.63, FDR q value < 10−6; pLNs, NES = 2.72, FDR q value < 10−6) in CD4 T cells on day 10 following infection compared to uninfected controls (Fig. 5B). This evidence concerns the gene CD4 and infection.