CD4 CM cells showed increased pyroptosis in blood on day 14 (P = 0.035), and in GALT and lymphoid tissues on day 10 following infection (for colon, P = 0.003; for mesenteric LNs, P = 0.004; for spleen, P = 0.005; for pelvic LNs, P = 0.008). The gene discussed is CD4; the disease is infection.