The CCA results indicated that tumor volume (P = 0.021), γδ T (P = 0.016), IL-17A (P = 0.044), IFN-γ (P = 0.033), and TLR4 (P = 0.01) were significant factors for the microbial community, implying that these factors are associated with the oral microbial community. This evidence concerns the gene IL17A and neoplasm.