ART4 and colon adenocarcinoma: Some of the relevant computed ADMETlab 2.0 parameters generated include human intestinal absorption (HIA), human colon adenocarcinoma cell lines (Caco-2) permeability, Madin–Darby canine kidney cells (MDCK) permeability, plasma glycoprotein (Pgp) inhibitor, plasma glycoprotein (Pgp) substrate, plasma protein binding (PPB), volume distribution (VD), blood–brain barrier (BBB) penetration, human cytochromes (CYP), clearance (CL), half-life (T1/2), AMES toxicity, carcinogenicity (Carc), eye irritation (EI), and respiratory toxicity (RT) as shown in Table 17.