Other studies from Morocco, South Korea, Brazil, concluded that MTHFR A1298C polymorphism affects male infertility and studies from Iran showed a link between the third polymorphism (G1793-A) and male infertility. Contradictory to this, different studies from Algeria, Poland, France, Italy, and China stipulated no relationship between the three SNPs and infertility in males. This evidence concerns the gene MTHFR and male infertility.