We subsequently assessed if the significant dysregulation of ACOX2 could be linked to the mutational status of the tumours, using TIMER2.0 we examined a number of genes commonly mutated in lung cancer (e.g. TP53) to determine whether mutations within these key genes were correlated with altered ACOX2 expression levels and the results are presented in Table 3. The gene discussed is TP53; the disease is lung carcinoma.