Pentadecanoylcarnitine also had dose-dependent tissue remodeling activities in two cell systems relevant to lung disease, fibrosis, and wound healing, including lowered plasminogen activation inhibitor 1 (PAI-1), matrix metallopeptidase 1 and 9 (MMP1, MMP9), and tissue plasminogen activator (tPA). The gene discussed is SERPINE1; the disease is lung disorder.