BCR and chronic myelogenous leukemia, BCR-ABL1 positive: However, in the whole transcriptome, the gene expression profile of Ph-positive myeloid leukemia cell lines (Supplemental Fig. 8a) and that of CML patients’ samples (Supplemental Fig. 8b) were substantially different from that of p210 or p190 BCR::ABL1 sublines and parental cells, regardless of whether cultured with GM-CSF or not.