Forty-three pathways were identified including cytokine–cytokine receptor interaction (p = 1.60E − 28), rheumatoid arthritis (p = 6.80E − 06), pathways in cancer (p = 9.30E − 06), intestinal immune network for IgA production (p = 3.50E − 05), JAK-STAT signaling pathway (p = 2.40E − 04), MAPK signaling pathway (p = 4.00E − 04), TGF-beta signaling pathway (p = 7.80E − 04), Toll-like receptor signaling pathway (p = 1.20E − 03), and nuclear factor (NF)-κB signaling pathway (p = 5.80E − 03) (Fig. 3A). Here, SOAT1 is linked to rheumatoid arthritis.