FLT3 and acute myeloid leukemia: We repeated this experiment in a primary FLT3-ITD + AML sample treated either with gilteritinib or DMSO at 10 nM for 6 h (Fig. 2G) and again found autophagy among the top KEGG pathway annotations enriched in phosphoproteins clustered by unsupervised co-expression clustering (Fig. 2H, I and Supplementary Fig. 4).