By analyzing the abundance of DC subtypes in the tumor microenvironment, we found that PIC + RT treatment increased the levels of CD103+CD11b− cDC1s and decreased the levels of CD11b+CD103− cDC2s in B78 melanoma tumors when compared with either untreated control or RT-alone treated tumors (Fig. 4e, f). The gene discussed is SLC25A3; the disease is neoplasm.