MRC1 and neoplasm: We found that tumor infiltration by TAMs (CD11b+F4/80+) as a percentage of myeloid cells (CD45+CD11b+) was not significantly influenced by the RT or PIC + RT treatment (Supplementary Fig. 20a, b), and the frequency of M1 macrophages (CD80+CD206−) among TAMs in radiated tumors was similar to that in PIC + RT group, with both exhibiting higher percentage of M1 macrophage when compared to untreated control mice (Fig. 4b and Supplementary Fig. 20c).