Notably, we found endothelial cells in stomach expressed major histocompatibility complex (MHC) class II genes such as HLA-DRA and HLA-DRB5 (Fig. 3c), which was confirmed by multicolor immunohistochemistry (IHC) staining on tumor sections from GC patients (Fig. 3d). This evidence concerns the gene HLA-DRB5 and neoplasm.