In newborns of pregnant mothers that experienced anxiety measured by PRAQ, a pregnancy-related anxiety questionnaire, researchers found that an increase in methylation of CpG islands of GABBR1 in the cord blood of male newborns (GABAB receptor subunit 1 gene), was associated with higher anxiety levels of pregnant mothers as well as increased cortisol levels in these infants on vaccination (applied stressor; Vangeel et al., 2017). This evidence concerns the gene GABBR1 and Anxiety.