Though no specific brain region or specific gene such as BDNF, was investigated in this study, the correlation of reduced global H3K9me2 and the observed decrease in anxiety-like behaviors, aligns with the study by Suri et al. (2013), where an increase in repressive H3K9me2 led to decreased hippocampal neurogenesis and overall cognitive decline. Here, BDNF is linked to Anxiety.