To investigate the relevance of LUCAT1 in the context of SARS-CoV-2 infections, we compared mRNAs regulated twofold or greater (up or down) upon LUCAT1 knockdown in THP1 cells with mRNAs regulated twofold or greater (up or down) in classic and intermediate monocytes during COVID-19 (scRNA-seq data). This evidence concerns the gene LUCAT1 and COVID-19.