ANGPTL3 and Fanconi anemia: Three genes are located in the vicinity of rs11208009 and SNPs in LD (r2 > 0.6): DOCK7, encoding a guanine nucleotide exchange factor important for neurogenesis (14); ANGPTL3, which encodes a growth factor specific for the vascular endothelium that is expressed specifically in the liver (15); and USP1, encoding a deubiquitinating enzyme specific for the Fanconi anemia pathway (16).