Correlation analysis of eGFR and CPT2, ACSL4, ACSL5, and ACSM5 expression levels in 201 healthy and CKD samples demonstrated that eGFR significantly negatively correlated with both ACSL4 and ACSL5 expression levels (P < 0.001) and positively correlated with CPT2 and ACSM5 (P < 0.0005). Here, ACSL5 is linked to chronic kidney disease.