NLRP3 and early-onset autosomal dominant Alzheimer disease: Aberrant activation of the NLRP3 inflammasome has been linked with several inflammatory disorders, such as cryopyrin-associated periodic syndromes, Alzheimer’s disease, diabetes, and atherosclerosis [23], as well as viral myocarditis, whereas the role of the NLRP3 inflammasome in viral myocarditis is controversial.