In patients with arthritis, the proliferative activity was not significantly elevated in any ICPs and slightly increased in cMo, CXCR5− DNB, PB, and PC (renal+: 1.142%, renal‐: 0.343%, P = 0.0069; renal+: 0.148%, renal‐: 0.059%, P = 0.0058; renal+: 0.191%, renal‐: 0.068%, P = 0.0031; and renal+: 0.024%, renal‐: 0.008%, P = 0.0032, respectively). This evidence concerns the gene CXCR5 and arthritic joint disease.