MKI67 and neoplasm: These include Ki67 assessment within tumour hotspots, defined as the area within an invasive tumour with the most Ki67‐positive cells by counting Ki67‐positive cells within a fixed number of tumour cells and calculate the percentage of positivity in the hotspot12; average expression of Ki67 expression within the whole tumour by scanning the whole slide at low power and estimating the percentage of positivity.13