CFTR and CFTR-related metabolic syndrome/CF screen positive, inconclusive diagnosis: Further outcomes, after CFTR genetic analysis introduction include the identification of carrier status [6] and the emergence of a cohort of infants with positive NBS test results but an inconclusive diagnosis, classified as having CF transmembrane conductance regulator-related metabolic syndrome (CRMS)/CF screen–positive, inconclusive diagnosis (CFSPID) [7,8].