In addition to oncogenic mutations of BRAF (10–35%) and NRAS (9–22%), which are mutually exclusive, as well as NF1 (11–23%), triple-wild-type driver mutations (45–58%) were observed [50] Bastian et al. [52] reported that genetic aberrations of KIT frequently occur in acral melanoma. Here, NRAS is linked to acral lentiginous melanoma.