Similarly, astrocyte-specific deletion of Kcnj10 using GFAP-cre mice results in premature lethality, epileptic seizures, and severe ataxia (Djukic et al., 2007), none of which were observed with Kir4.1 deletion using Fabp7-CreER2 mice. This evidence concerns the gene KCNJ10 and cerebellar ataxia.