Compared with the nonheart failure group, the heart failure group exhibited higher levels of β2-MG, hypersensitive TNI, pro-BNP, EDV (CF/BSA), ESV (CF/BSA), myocardial mass (CF/BSA), basal ECV, apical ECV, and mid ECV (all p < 0.05). The gene discussed is NPPB; the disease is heart failure.