TRH and meningioma: As shown in Figure 7A, high levels of TRH mRNA were found in all transfected HBL-52 cells, even those transfected with empty plasmid, but FGF3 mRNA appeared only in cells transfected with KLF4K409Q-expressing plasmid, indicating that a meningioma cell line with mutated TRAF7 and ectopically expressed KLF4K409Q can produce FGF3 mRNA.