TG and LDL-c were higher in the positive TPOAb with GDM group (1.92 ± 0.79 mmol/L, 2.82 ± 0.72 mmol/L, respectively; P < 0.05) In addition, sCD40L levels were the highest in positive TPOAb with GDM group compared to other 3 groups. This evidence concerns the gene CD40LG and gestational diabetes.