To be specific, we found that CARTPT (logFC: -2.84) and EPHA5 (logFC: -1.18) were significantly downregulated in AD (GSE122063), and they had a good performance as a marker of the disease (GSE122063; the AUC of CARTPT was 0.969; the AUC of EPHA5 was 0.739). The gene discussed is EPHA5; the disease is Alzheimer disease.