Finally, we investigated the expression levels of the common mutated genes (JMJD1C, MUC16, PDZD2, RYR1, and SLA) in papillary thyroid cancer cell lines (K1, TPC-1 and BCPAP) compared to an immortalized normal thyroid epithelial cell line (Nthy-ori 3-1) by qRT-PCR. This evidence concerns the gene RYR1 and thyroid gland papillary carcinoma.