Firstly, this study collected a lot of clinical indicators, including maximum tumor diameter,ascites,carcinoembryonic antigen, glycosyl antigen 125, glycosyl antigen 153, glycosyl antigen 199, squamous cell carcinoma-associated antigen, serum human chorionic gonadotropin, human epididymal epithelial secretory protein 4, alpha-fetoprotein, the Premenopausal ROMA index and the Postmenopausal ROMA index. The gene discussed is CEACAM5; the disease is squamous cell carcinoma.