Particularly, SOCS2 gene was obviously decreased in HCC tissues and radioresistant SK-Hep-1R cells compared with normal tissues and SK-Hep-1 cells (Fig. 1E), while a low expression of SOCS2 referred to a poor prognosis of HCC patients according to the Kaplan–Meier overall survival (OS) analysis with GEPIA (Fig. 1F). Here, SOCS2 is linked to hepatocellular carcinoma.