For instance, Zhong et al. have identified CNA-related lncRNAs that can better predict cervical cancer prognosis18, Athie et al. shown that the lncRNA ALAL-1 could be used as a regulator of lung cancer immune evasion via CNA analysis19, and Zhong et al. revealed the prognosis-related lncRNAs by analyzing the expression profiles of lncRNAs and CNAs in bladder cancer20, however, few studies have explored the regulatory relationships between lncRNAs and CNAs in liver cancer, and the CNA-related lncRNA prognostic model in liver cancer is largely unknown. Here, IKBKB-DT is linked to liver cancer.