CD4 and cancer: In the multivariable logistic regression model, using HCDR as the comparator, PCDR showed a largely increased risk of failing to achieve nAbs > 1:10, after adjusting for the main identified confounders (age, time from HIV diagnosis, CD4 nadir, HIV-RNA < 50 vs > 50 copies/mL at the time of third dose, days from the date of 2nd dose, vaccine sequence and concomitant cancer), although not statistically significant [aOR 5.04 (95% CI 0.22, 115.1); p = 0.31] (Table 2).