MYBL2 and COVID-19: For example, the eQTL effect of rs285171 on MYBL2 gene diminished in samples with severe and most severe COVID-19 symptoms (Fig. 7e), where such interaction was not replicated in neutrophil ieQTL analysis in GTEx (of note, MYBL2 gene is known to be involved in stress responses61,62 and is only lowly expressed in neutrophils; Fig. S20).