INS and obesity due to melanocortin 4 receptor deficiency: Areas of greater deprivation had a higher use of antiepileptics, drugs for opioid dependence, and insulin, in keeping with what we know of the relationship of epilepsy [34, 35], substance abuse [36], diabetes and obesity [37] with socioeconomic deprivation and increased use of chronic/long-term medication in those with low education [8] and income [10].