In addition, we observed a significant upregulation of NEK6 but not NEK7 transcripts in peripheral blood mononuclear cells (PBMCs) from 10 ALS patients carrying C9orf72 repeat expansions compared to 10 healthy controls and 10 sporadic ALS patients (Table S3, Figure 3C). Here, C9orf72 is linked to amyotrophic lateral sclerosis.