We also found that NEK6 expression is dysregulated in blood cells and postmortem brain tissues of C9orf72 patients, further substantiating an important role for NEK6 in C9orf72-related neurodegeneration and identifying a potential new biomarker for C9orf72 FTD/ALS. The gene discussed is C9orf72; the disease is amyotrophic lateral sclerosis.