Additionally, 23 genes (HOMER1, EZH2, CHEK1, TYMS, NOS2, CDK1, TOP2A, SLC9A3, etc.)were overexpressed in the tumor group while 31 genes (PROK2, ADORA2A, NPAS2, SREBF1, ATOH7, PER1, NTRK1, HOMER1, etc.)were downregulated. This evidence concerns the gene TOP2A and neoplasm.