RPL4P4 and central nervous system cancer: Figure 6(a) shows that RPL4P4 expression is positively correlated with the infiltration of neutrophils, M0 and M2 macrophages, eosinophils, DCs, and Treg T cells in gliomas. It was inversely correlated with mast cell and B cell infiltrates. Next, we investigated the relationship between RPL4P4 and tumor purity based on the ESTIMATE algorithm. In gliomas, RPL4P4 expression was positively correlated with stromal score, immune score, and ESTIMATE score (Figure 6(c)). RPL4P4 was also positively correlated with tumor mutation burden (TMB) (Figure 6(d)).