Microdeletions encompassing NR4A2 and point mutations resulting in haploinsufficiency in NR4A2 have been previously reported in individuals with ID and language impairments, suggesting the role of NR4A2 in human NDD (Reuter et al., 2017; Levy et al., 2018; Ramos et al., 2019). The gene discussed is NR4A2; the disease is Neurodevelopmental delay.