LPL and B-cell chronic lymphocytic leukemia: Limitations of our study include the following: (1) the study is observational; (2) we have not explored any of the potential mechanisms discussed, including the levels of LPL or lipoprotein receptors in CLL cell samples; and (3) while we conducted a comprehensive NMR-based lipoprotein characterization, we have not determined the entire circulating metabolome, including different fatty acid levels, to provide additional information about energy utilization.