The CNVkit SCNA analysis also highlights the potential importance of oncogenes (e. g., RCP, CD44, WT1, BCL2L2, and AKT2) and tumor suppressors (e. g., PRKCDBP) to TNBC etiology and metastatic progression, as significant amplicons/deleted regions harbor these genes. The gene discussed is AKT2; the disease is neoplasm.